Conasprella mcgintyi is a species of predatory sea snail, a marine gastropod mollusk in the family Conidae, the cone snails, cone shells or cones. Like all species within the genus Conasprella, these cone snails are predatory and venomous. They are capable of stinging humans; therefore, live ones should be handled carefully or not at all.

Distribution This is a western Atlantic species, which occurs from Florida to Brazil, as well as in the Gulf of Mexico.

Description Conasprella mcgintyi has elongate, many-whorled shell with a high conical spire. The external coloration is white with orange markings. The maximum recorded shell length is 52.2 mm.

Habitat Minimum recorded depth is 55 m. Maximum recorded depth is 219 m.