Sepiella inermis is a species of cuttlefish in the family Sepiidae. It is indigenous to the Indo-Pacific region. In this region, S. inermis is an economically important species, and is sold and eaten.

Description Sepiella inermis is a relatively small species of cuttlefish, with an average mantle length of about 50mm, with a maximum length of about 125mm. It has narrow fins and a moderately small, ovate shell that is white, with a brown and polished horny margin. The dorsal surface of S. inermis ranges in color depending on chromatophores present, ranging from gray-brown to purple, with the ventral surface being light gray or brown. The dorsolateral surface of the mantle is adorned with a series of white spots in both males and females.

Distribution Sepiella inermis is found throughout the Indo-Pacific region, from shallow water down to depths of about 40m. This species lives primarily benthically.

Reproduction and Development Sepiella inermis spawns throughout the year.