Sepia bertheloti, the African cuttlefish, is a species of cuttlefish from the family Sepiidae which is found in the warmer waters of the eastern Atlantic Ocean off Africa.

Description Sepia bertheloti grows to a mantle length of 175mm in males and 134mm in females. The dorsal anterior mantle margin forms a triangular lobe between the eyes. The wide fines have a wide gap between them at the rear. The males have a hectocotylus on the left ventral arm and this has one or two rows of normal size suckers at the base, nine to thirteen rows of highly shrunken suckers in the middle part of the arm; these suckers are arranged in two dorsal and two ventral series which are laterally displaced and are separated by a gap. The suckers on the hectocotylus are covered by a well developed dorsal protective membrane. The tentacular club is straight and slender having five or six suckers in transverse rows in which a number of the suckers of the inner two or three rows are larger than rest. The cuttlebone is oblong in shape, outline roughly rectangular; tapering to a point anteriorly and rounded and blunt posteriorly. Its dorsal surface is evenly convex and covered with a sculpture of calcareous granulose arranged in a net like pattern which have their greatest concentration in the middle of the bone and at the long edges where they are arranged in irregular ridges parallel to the margin. The bone is most calcified at the rear and there is an indistinct dorsal median rib which broadens slightly towards the head end.