Chrysaora chesapeakei is a sea nettle from the family Pelagiidae. It was shown to be a distinct species from Chrysaora quinquecirrha in 2017. Since then, it is also commonly known as the bay nettle. It is found mainly in estuaries of the eastern coast of the U.S.A and is especially known from the Chesapeake Bay, but can also be found in the open Gulf of Mexico.

Description Similar to other species of sea nettle, C. chesapeakei has a centrally located mouth surrounded by oral arms. It has a vaguely saucer-like shaped bell and typically has four long, lacy oral arms hanging from the bell. They usually have around twenty-four tentacles. The tentacles do contain a toxin that is capable of stinging and causing pain to humans. However, the toxin is not strong enough to prove fatal to a human, unless the toxin were to cause an allergic reaction. In 2017, C. chesapeakei was differentiated as a separate species from C. quinquecirrha based on genetic and morphological differences.